When it comes to the Winchesters, Castiel has kind of always had a favorite.
Its no secret that his friendship with Dean is stronger than his friendship with Sam.
Sam and Cas have never had that same connection, Misha Collins says.

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It was formed the moment that Cas pulled Dean out of Hell.
Cas is pulling out all the stops, Collins says.
Hes willing to make any kind of deal with any kind of devil for get Dean back.
Hes attempting to form unsavory alliances and leaving no stone unturned.
The entire hunter clan is wildly searching for any possible solution to the problem.
Jared Padalecki adds, Sam is grateful in a strange way almost to have something to do.
They have grown closer over the years and we see that in the beginning of this season.
Theyre showing care and concern for one another to an extent that we havent quite seen before.
After all, theyve both lost a brother.
But dont worry, Dean wont be gone forever.
Supernaturalreturns Thursday, Oct. 11 at 8 p.m.
ET on The CW.