But as their fans know well, they often take their chemisty off screen.
Check out our favorite moments ahead.
Matt Slocum/AP/REX/Shutterstock
Gilbert Carrasquillo/Getty Images
George Pimentel/WireImage
Eric Charbonneau/Invision/AP/REX/Shutterstock
Chelsea Lauren/Variety/REX/Shutterstock
Eric Charbonneau/Invision/AP/REX/Shutterstock
Joel Ryan/Invision/AP/REX/Shutterstock
Paras Griffin/Getty Images
Paras Griffin/Getty Images
George Pimentel/WireImage
Kevin Winter/Getty Images
Dave Allocca/Starpix/REX/Shutterstock
Barry Wetcher/Metro Goldwyn Mayer Pictures
Barry Wetcher/Metro Goldwyn Mayer Pictures
Barry Wetcher/Metro Goldwyn Mayer Pictures
Barry Wetcher/Metro Goldwyn Mayer Pictures
Warner Bros. Pictures
Barry Wetcher/Metro Goldwyn Mayer Pictures
Warner Bros. Pictures
Barry Wetcher/Warner Bros.
