Thats been clear since the first season.
(Spoiler alert: Nothing good!)
shes the Meat-Face monster Jessica remembered in the premiere).

Credit: David Giesbrecht/Netflix
Unfortunately, they cant fix Alisas anger problems.
Every time she gets pissed off, she flies off the handle and starts destroying things.
During this period of time, Karl has also taken a special interest in Alisa.
Theres something creepy about the way he relates to her.
He clearly has feelings for her since shes his big scientific experiment.
This sends Alisa flying off the handle, but Karl sedates her before she kills anyone.
However, Alisa doesnt give up.
Alisa escapes IGH to go find her daughter.
She still has an edge and loves her brown liquor.
Both seem very unnecessary.
Thats probably one of the major weaknesses of the episode.
The presence of Stirling feels like a last-minute, shameless retcon.
However, Jessica cuts their meeting short when Stirling brings up Trish investing in his club.
Naturally, Jessica steps in and kicks their butts.
Meanwhile, Alisa is hot on her daughters trail.
She checks in with Dorothy first, who is able to point her in the right direction.
Jessica offers to buy Alisa a drink in return for the tampon.
Stirlings investors offer to forgive his debt if he convinces Jessica to come work for them.
Because hes the worst, Stirling agrees.
Jessica arrives in time just to find her boyfriend dead on the ground, unaware of what actually happened.
Did the show need to add yet another traumatic event like this to Jessicas past?
No, it didnt.
Theres a tenderness in their scene that hints at how close theyll become in the future.
From there the episode returns to the present, and Alisa asks Jessica if she could ever forgive her.
Jessica responds by punching her, but Karl sedates Jessica before she can go any further.