See 12 of our favorites, ahead.
Hanks and Ryan remained friends for years and finally reunited on the big screen in 2015 withIthaca.
Leonardo DiCaprio and Kate Winslet
We’ll never let go of Rose and Jack.
Ron Batzdorff/Touchstone; Brian Hamill/Warner Bros.; Jojo Whilden/The Weinstein Company
Leonardo DiCaprio and Kate Winslet were an Oscar-worthy pair inTitanicin 1997.
A decade later they worked together once more, appearing in 2008’sRevolutionary Road.
Matthew McConaughey and Kate Hudson
Kate Hudson hardly lost Matthew McConaughey in any short amount of time.
Brain Hamill/Warner Bros.
Nearly a decade later, they sprinted down the aisle inRunaway Bride(1999).
They fell in love once more in 2004 with50 First Datesand continued the love in 2014 withBlended.
They became Ian and Toula once more forMy Big Fat Greek Wedding 2in 2016.
Paramount
Jon Hamm and Kristen Wiig
Jon Hamm and Kristen Wiig were an onscreen couple twice in 2011.
They played Ben and Missy inFriends with Kidsand Ted and Annie inBridesmaids.
Michael Gibson/Paramount
Ron Batzdorff
Ben Glass/ Warner Bros.
Alex Bailey
New Line Cinema/Everett Collection
S. Baldwin/ New Line Cinema
Jojo Whilden/ The Weinstein Company
Everett Collection
Courtesy Everett Collection
Jojo Whilden
